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Clinical and pathological characteristics of breast cancer The clinical presentation can vary from a painless palpable breast mass to more advanced symptoms such as skin changes, nipple discharge, or local pain, with or without palpable axillary mass, nipple discharge and inversion, and breast skin thickening

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It is often accompanied by chronic fatigue, muscle loss, osteoporosis, depressive states or increased risk of cardiometabolic disorders

Growth hormone: roles in male reproduction

10.1126/science.aac4690 Science 105 KimS.-M.ZhangS.ParkJ.SungH